靶标：
KATNA1
产品别名：
KATNA1； katanin catalytic subunit A1； katanin catalytic subunit A1； katanin p60 ATPase-containing subunit A1； katanin p60 (ATPase containing) subunit A 1； katanin p60 subunit A1； p60 katanin； 剑蛋白p60亚基A1； 剑蛋白P60亚基A1(KATNA1)；
背景信息：
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified.
