靶标:
LILRA2
产品别名:
CD85H; ILT1; LIR-7; LIR7; LILRA2; leukocyte immunoglobulin like receptor A2; leukocyte immunoglobulin like receptor A2; leukocyte immunoglobulin-like receptor subfamily A member 2; CD85 antigen-like family member H; immunoglobulin-like transcript 1; leucocyte Ig-like receptor A2; leukocyte immunoglobulin-like receptor 7; leukocyte immunoglobulin-like receptor subfamily A member 2 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2; 白细胞免疫球蛋白样受体亚家族A成员2(LILRA2);
背景信息:
This gene encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and there is a pseudogene for this gene on chromosome 3. [provided by RefSeq, Mar 2014],