靶标:
FASTK
产品别名:
FAST; FASTK; Fas activated serine/threonine kinase; Fas activated serine/threonine kinase; fas-activated serine/threonine kinase; FAST kinase; Fas活化的丝/苏氨酸激酶; Fas激活丝氨酸/苏氨酸激酶(FASTK);
背景信息:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],