靶标:
CORIN
产品别名:
ATC2; CRN; Lrp4; PEE5; TMPRSS10; CORIN; corin, serine peptidase; corin, serine peptidase; atrial natriuretic peptide-converting enzyme; heart-specific serine proteinase ATC2; pro-ANP-convertase; pro-ANP-converting enzyme; transmembrane protease serine 10; Corin蛋白(CRN); 心脏特异性丝氨酸蛋白酶;
背景信息:
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.