靶标:
GLRX3
产品别名:
GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3; GLRX3; glutaredoxin 3; glutaredoxin 3; glutaredoxin-3; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; PKCq-interacting protein; glutaredoxin 4; testicular tissue protein Li 75; thioredoxin-like protein 2; 谷氧还蛋白3(GLRX3);
背景信息:
Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.