靶标:
PPIH
产品别名:
CYP-20; CYPH; SnuCyp-20; USA-CYP; PPIH; peptidylprolyl isomerase H; peptidylprolyl isomerase H; peptidyl-prolyl cis-trans isomerase H; PPIase h; U-snRNP-associated cyclophilin SnuCyp-20; U-snRNP-associated cyclophilin SunCyp-20; USA-CyP SnuCyp-20; cyclophilin H; rotamase H; small nuclear ribonucleoprotein particle-specific cyclophilin H;
背景信息:
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.