靶标：
SAP18
产品别名：
2HOR0202； SAP18P； SAP18； Sin3A associated protein 18； Sin3A associated protein 18； histone deacetylase complex subunit SAP18； 18 kDa Sin3-associated polypeptide； Sin3A-associated protein, 18kDa； cell growth inhibiting protein 38； cell growth-inhibiting gene 38 protein； epididymis secretory sperm binding protein； histone deacetlyase complex subunit SAP18； sin3-associated polypeptide, 18 kDa； sin3-associated polypeptide, p18； 组蛋白去乙酰化酶复合亚基SAP18；
背景信息：
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008],
