靶标：
PRG4
产品别名：
CACP； HAPO； JCAP； MSF； SZP； PRG4； proteoglycan 4； proteoglycan 4； proteoglycan 4； articular superficial zone protein； hemangiopoietin； lubricin； megakaryocyte stimulating factor； superficial zone proteoglycan； 巨核细胞刺激因子/蛋白多糖4/浅表层粘膜蛋白多糖； 蛋白聚糖4(PRG4)；
背景信息：
The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.
