靶标：
LPCAT3
产品别名：
C3F； LPCAT； LPLAT 5； LPSAT； MBOAT5； OACT5； nessy； LPCAT3； lysophosphatidylcholine acyltransferase 3； lysophosphatidylcholine acyltransferase 3； lysophospholipid acyltransferase 5； 1-acylglycerophosphocholine O-acyltransferase； 1-acylglycerophosphoethanolamine O-acyltransferase； 1-acylglycerophosphoserine O-acyltransferase； O-acyltransferase (membrane bound) domain containing 5； O-acyltransferase domain-containing protein 5； lyso-PC acyltransferase 3； lyso-PS acyltransferase； lysophosphatidylserine acyltransferase； membrane bound O-acyltransferase domain containing 5； membrane-bound O-acyltransferase domain-containing protein 5； putative protein similar to nessy； 溶血卵磷脂酰基转移酶3(LPCAT3)；
背景信息：
Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
