靶标:
PLXNC1
产品别名:
CD232; PLXN-C1; VESPR; PLXNC1; plexin C1; plexin C1; plexin-C1; plexin (semaphorin receptor); receptor for viral semaphorin protein; receptor for virally-encoded semaphorin; virus-encoded semaphorin protein receptor; 细胞表面蛋白CD232;
背景信息:
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011],