羧基端小结构域磷酸酶2抗体

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羧基端小结构域磷酸酶2抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Anti-CTDSP2
Anti-CTD small phosphatase 2 Antibody

靶标：

CTDSP2

产品别名：

OS4； PSR2； SCP2； CTDSP2； CTD small phosphatase 2； CTD small phosphatase 2； carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2； CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2； NLI-interacting factor 2； conserved gene amplified in osteosarcoma； nuclear LIM interactor-interacting factor 2； protein OS-4； small C-terminal domain phosphatase 2； small CTD phosphatase 2；羧基端小结构域磷酸酶2；

背景信息：

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.