靶标:
SNUPN
产品别名:
KPNBL; RNUT1; Snurportin1; SNUPN; snurportin 1; snurportin 1; snurportin-1; RNA U transporter 1; Snurportin 1蛋白(SNUPN1);
背景信息:
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.