靶标:
TOM1L1
产品别名:
SRCASM; TOM1L1; target of myb1 like 1 membrane trafficking protein; target of myb1 like 1 membrane trafficking protein; TOM1-like protein 1; src-activating and signaling molecule protein; target of Myb-like protein 1; Src激活和信号分子蛋白;
背景信息:
function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,