靶标：
PARP2
产品别名：
ADPRT2； ADPRTL2； ADPRTL3； ARTD2； PARP-2； pADPRT-2； PARP2； poly(ADP-ribose) polymerase 2； poly(ADP-ribose) polymerase 2； poly [ADP-ribose] polymerase 2； ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2； ADP-ribosyltransferase diphtheria toxin-like 2； ADPRT-2； DNA ADP-ribosyltransferase PARP2； NAD(+) ADP-ribosyltransferase 2； hPARP-2； poly (ADP-ribose) polymerase family, member 2； poly (ADP-ribosyl) transferase-like 2； poly[ADP-ribose] synthase 2； poly[ADP-ribose] synthetase 2； protein poly-ADP-ribosyltransferase PARP2； 多腺苷二磷酸多聚酶PARP2；
背景信息：
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008],
