靶标：
NOS1AP
产品别名：
6330408P19Rik； CAPON； NPHS22； NOS1AP； nitric oxide synthase 1 adaptor protein； nitric oxide synthase 1 adaptor protein； carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein； C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON)； C-terminal PDZ ligand of neuronal nitric oxide synthase protein； ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain； nitric oxide synthase 1 (neuronal) adaptor protein； 一氧化氮合酶1衔接蛋白(NOS1AP)； 神经型一氧化氮合成酶结合蛋白；
背景信息：
Nitric oxide synthase 1 adaptor protein (NOS1AP) also known as carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (CAPON) is a protein that in humans is encoded by the NOS1AP gene. This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms
