靶标:
ATP5MJ
产品别名:
6.8PL; ATP5MPL; C14orf2; MLQ; MP68; PLPM; ATP5MJ; ATP synthase membrane subunit j; ATP synthase membrane subunit j; ATP synthase subunit ATP5MJ, mitochondrial; 6.8 kDa mitochondrial proteolipid protein; 6.8-kDa proteolipid with N-terminal sequence Met-Leu-Gln (MLQ); ATP synthase membrane subunit 6.8PL; ATP synthase subunit ATP5MPL, mitochondrial;
背景信息:
C14orf2, also known as MP68, MP68 is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.