靶标:
BAG5
产品别名:
BAG-5; CMD2F; BAG5; BAG cochaperone 5; BAG cochaperone 5; BAG family molecular chaperone regulator 5; BCL2 associated athanogene 5; bcl-2-associated athanogene 5; Bcl2关联永生基因5(BAG5); BCL2分子伴侣调节蛋白5;
背景信息:
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],