靶标:
TBPL1
产品别名:
MGC:8389; MGC:9620; STUD; TLF; TLP; TRF2; TBPL1; TATA-box binding protein like 1; TATA-box binding protein like 1; TATA box-binding protein-like 1; 21-kDA TBP-like protein; TATA box-binding protein-like protein 1; TATA box-binding protein-related factor 2; TBP-like 1; TBP-related factor 2; TBP-related protein; second TBP of unique DNA protein; TATA盒结合蛋白样蛋白1;
背景信息:
This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.