靶标:
MAGED1
产品别名:
DLXIN-1; NRAGE; MAGED1; MAGE family member D1; MAGE family member D1; melanoma-associated antigen D1; MAGE tumor antigen CCF; MAGE-D1 antigen; melanoma antigen family D, 1; melanoma antigen family D1; neurotrophin receptor-interacting MAGE homolog; 黑色素瘤相关抗原D1;
背景信息:
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],