靶标：
HAND2
产品别名：
DHAND2； Hed； Thing2； bHLHa26； dHand； HAND2； heart and neural crest derivatives expressed 2； heart and neural crest derivatives expressed 2； heart- and neural crest derivatives-expressed protein 2； basic helix-loop-helix transcription factor HAND2； class A basic helix-loop-helix protein 26； deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2； 心脏和神经嵴衍生蛋白2；
背景信息：
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008],
