靶标：
DDX23
产品别名：
PRPF28； SNRNP100； U5-100K； U5-100KD； prp28； DDX23； DEAD-box helicase 23； DEAD-box helicase 23； probable ATP-dependent RNA helicase DDX23； 100 kDa U5 snRNP-specific protein； DEAD (Asp-Glu-Ala-Asp) box polypeptide 23； DEAD box protein 23； PRP28 homolog, yeast； PRP28p homolog； U5 snRNP 100 kD protein； U5 snRNP-specific 100-kD protein； 三磷酸腺苷依赖解旋酶DDX23；
背景信息：
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
