靶标:
NMT2
产品别名:
NMT2; N-myristoyltransferase 2; N-myristoyltransferase 2; glycylpeptide N-tetradecanoyltransferase 2; NMT 2; myristoyl-CoA:protein N-myristoyltransferase 2; peptide N-myristoyltransferase 2; protein-lysine myristoyltransferase NMT2; type II N-myristoyltransferase; 肉豆蔻酰基转移酶2-N端肽;
背景信息:
This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl group to the N-terminal glycine residue of many signaling proteins, including the human immunodeficiency virus type 1 (HIV-1) proteins, Gag and Nef. Alternative splicing results in multiple transcript variants.