靶标:
TRIP10
产品别名:
CIP4; HSTP; STOT; STP; TRIP-10; TRIP10; thyroid hormone receptor interactor 10; thyroid hormone receptor interactor 10; cdc42-interacting protein 4; TR-interacting protein 10; protein Felic; salt tolerant protein; salt tolerator; thyroid receptor-interacting protein 10; 细胞分化周期CDC42相互作用蛋白4;
背景信息:
Cdc42-interacting protein 4 is a protein that in humans is encoded by the TRIP10 gene. TRIP10 (thyroid hormone receptor interactor 10), also known as CIP4 (Cdc42-interacting protein 4), is a novel adaptor protein which may be invloved in plasma membrane remodeling. CIP4 has been reported to negatively regulate glucose uptake by promoting GLUT4 endocytosis in muscle cells. At least five splice variants for human CIP4 have been identified, including CIP4a (CIP4), CIP4b (FELIC), CIP4c, CIPh (CIP4/2). Western blot analysis usually demonstrates a major band around 75 kDa and a weaker band about 85 kDa.