靶标:
ADGRG1
产品别名:
BFPP; BPPR; GPR56; TM7LN4; TM7XN1; ADGRG1; adhesion G protein-coupled receptor G1; adhesion G protein-coupled receptor G1; adhesion G-protein coupled receptor G1; 7-transmembrane protein with no EGF-like N-terminal domains-1; G protein-coupled receptor 56; testicular tissue protein Li 77; 蛋白偶联受体56;
背景信息:
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],