靶标:
UBE2L6
产品别名:
RIG-B; UBCH8; UBE2L6; ubiquitin conjugating enzyme E2 L6; ubiquitin conjugating enzyme E2 L6; ubiquitin/ISG15-conjugating enzyme E2 L6; E2 ubiquitin-conjugating enzyme L6; retinoic acid induced gene B protein; ubiquitin carrier protein L6; ubiquitin conjugating enzyme E2L 6; ubiquitin-protein ligase L6; 泛素载体蛋白L6;
背景信息:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011],