靶标:
MSC
产品别名:
ABF-1; ABF1; MYOR; bHLHa22; MSC; musculin; musculin; musculin; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; class A basic helix-loop-helix protein 22; 活化B淋巴细胞因子1;
背景信息:
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008],