靶标:
LRRFIP1
产品别名:
FLAP-1; FLAP1; FLIIAP1; GCF-2; GCF2; HUFI-1; TRIP; LRRFIP1; LRR binding FLII interacting protein 1; LRR binding FLII interacting protein 1; leucine-rich repeat flightless-interacting protein 1; GC-binding factor 2; LRR FLII-interacting protein 1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; leucine rich repeat (in FLII) interacting protein 1; 亮氨酸丰富重复FLII相互作用蛋白1(LRRFIP1); 巨噬细胞调控相关蛋白LRRFIP1;
背景信息:
developmental stage:Widely expressed in fetal tissues.,function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the LRRFIP family.,subunit:Interacts with FLII.,tissue specificity:Ubiquitously expressed.,