靶标:
CH25H
产品别名:
C25H; CH25H; cholesterol 25-hydroxylase; cholesterol 25-hydroxylase; cholesterol 25-hydroxylase; cholesterol 25-monooxygenase; h25OH; 胆固醇-25-羟化酶(CH25H); 胆固醇25羟化酶;
背景信息:
Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.