靶标:
KALRN
产品别名:
ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD; KALRN; kalirin RhoGEF kinase; kalirin RhoGEF kinase; kalirin; huntingtin-associated protein interacting protein (duo); serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; 舞蹈症相关蛋白KALRN;
背景信息:
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016],