靶标：
PER3
产品别名：
FASPS3； GIG13； PER3； period circadian regulator 3； period circadian regulator 3； period circadian protein homolog 3； cell growth-inhibiting gene 13 protein； circadian clock protein PERIOD 3； period circadian clock 3； period circadian protein 3； 生物钟蛋白3；
背景信息：
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014],
