靶标:
IL18R1
产品别名:
CD218a; CDw218a; IL-18R-alpha; IL-18Ralpha; IL-1Rrp; IL18RA; IL18Ralpha2; IL1RRP; IL18R1; interleukin 18 receptor 1; interleukin 18 receptor 1; interleukin-18 receptor 1; CD218 antigen-like family member A; IL1 receptor-related protein; cytokine receptor; interleukin-18 receptor alpha; 白介素18受体1(IL18R1); 白细胞介素-18受体α链;
背景信息:
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],