靶标:
AOC3
产品别名:
HPAO; SSAO; VAP-1; VAP1; AOC3; amine oxidase copper containing 3; amine oxidase copper containing 3; membrane primary amine oxidase; amine oxidase, copper containing 3 (vascular adhesion protein 1); copper amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; 含铜胺氧化酶3(AOC3); 血管粘附蛋白1;
背景信息:
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013],