靶标:
USO1
产品别名:
P115; TAP; VDP; USO1; USO1 vesicle transport factor; USO1 vesicle transport factor; general vesicular transport factor p115; USO1 vesicle docking protein homolog; transcytosis associated protein; vesicle docking protein p115; 囊泡对接蛋白p115;
背景信息:
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],