靶标:
RGS5
产品别名:
MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129; RGS5; regulator of G protein signaling 5; regulator of G protein signaling 5; regulator of G-protein signaling 5; regulator of G-protein signalling 5; G蛋白信号转导调节因子5; 蛋白信号调节因子5(RGS5);
背景信息:
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011],