靶标:
TPST1
产品别名:
TANGO13A; TPST1; tyrosylprotein sulfotransferase 1; tyrosylprotein sulfotransferase 1; protein-tyrosine sulfotransferase 1; TPST-1; transport and golgi organization 13 homolog A; 酪蛋白硫酸转移酶1;
背景信息:
The tyrosylprotein sulfotransferases TPST-1 and TPST-2 catalyze the sulfation of tyrosine residues within secreted and membrane-bound proteins, such as cell adhesion molecules, G-protein-coupled receptors, coagulation factors, serpins, extracellular matrix proteins, and hormones. Although both TPST-1 and TPST-2 utilize 3!?-phosphoadenosine 5!?-phosphosulfate as their sulfate donor, they differ in their substrate specificity.