靶标:
H3C4
产品别名:
H3/b; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C6; H3C7; H3C8; H3FB; HIST1H3D; H3C4; H3 clustered histone 4; H3 clustered histone 4; histone H3.1; H3 histone family, member B; histone 1, H3d; histone H3/b; histone cluster 1 H3 family member d; histone cluster 1, H3d;
背景信息:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Dai J, et al. (2005) Genes Dev 19(4): 472-488.
Yih LH, et al. (2005) Carcinogenesis 26(1): 53-63.