靶标：
FZD8
产品别名：
FZ-8； hFZ8； FZD8； frizzled class receptor 8； frizzled class receptor 8； frizzled-8； frizzled 8, seven transmembrane spanning receptor； frizzled family receptor 8； frizzled homolog 8； 卷曲蛋白8；
背景信息：
frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],
