靶标：
AIMP2
产品别名：
HLD17； JTV-1； JTV1； P38； AIMP2； aminoacyl tRNA synthetase complex interacting multifunctional protein 2； aminoacyl tRNA synthetase complex interacting multifunctional protein 2； aminoacyl tRNA synthase complex-interacting multifunctional protein 2； ARS-interacting multi-functional protein 2； multisynthase complex auxiliary component p38； multisynthetase complex auxiliary component p38； protein JTV-1；
背景信息：
AIMP2, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, also known as AIMP2, is an enzyme that in humans is encoded by the AIMP2 gene. AIMP2 encodes a predicted 312-amino acid protein. The AIMP2 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. AIMP2 and HRI overlap slightly and are arranged in a tail-to-tail fashion. AIMP2 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. AIMP2 is transcribed in the opposite direction compared to HRI and PMS2. AIMP2 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex. AIMP2 can work as a mediator of TGF-beta signaling and its functional importance in the control of MYC during lung differentiation.
