靶标:
CNBP
产品别名:
CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9; CNBP; CCHC-type zinc finger nucleic acid binding protein; CCHC-type zinc finger nucleic acid binding protein; CCHC-type zinc finger nucleic acid binding protein; cellular nucleic acid-binding protein; erythroid differentiation-related; sterol regulatory element-binding protein; zinc finger protein 273; zinc finger protein 9 (a cellular retroviral nucleic acid binding protein); 细胞核酸结合蛋白;
背景信息:
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016],