靶标:
ZIC3
产品别名:
HTX; HTX1; VACTERLX; ZNF203; ZIC3; Zic family member 3; Zic family member 3; zinc finger protein ZIC 3; Zic family member 3 (odd-paired homolog, Drosophila); heterotaxy 1; zinc finger protein 203; zinc finger protein of the cerebellum 3; 内脏异位相关蛋白/锌指蛋白203;
背景信息:
ZIC3 is a member of the Zinc finger of the cerebellum (ZIC) protein family. This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.