靶标:
WNT2B
产品别名:
WNT13; WNT2B; Wnt family member 2B; Wnt family member 2B; protein Wnt-2b; XWNT2, Xenopus, homolog of; wingless-type MMTV integration site family, member 13; wingless-type MMTV integration site family, member 2B; 信号通路Wnt2B; 无翅型MMTV整合位点家族成员2B(WNT2B);
背景信息:
WNT2B (Wingless-Type MMTV Integration Site Family Member 2B), is a protein that in humans is encoded by the WNT2B gene. This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. Katoh et al. (1996) used fluorescence in situ hybridization to map the WNT13 gene to chromosome 1p13. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis.