靶标:
VPREB1
产品别名:
CD179a; IGI; IGVPB; VPREB; VPREB1; V-set pre-B cell surrogate light chain 1; V-set pre-B cell surrogate light chain 1; immunoglobulin iota chain; CD179 antigen-like family member A; pre-B lymphocyte 1; v(pre)B protein; B淋巴细胞前体蛋白1; 前-B-淋巴细胞基因1(VPREB1);
背景信息:
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],