靶标:
VIPR1
产品别名:
HVR1; II; PACAP-R-2; PACAP-R2; RDC1; V1RG; VAPC1; VIP-R-1; VIPR; VIRG; VPAC1; VPAC1R; VPCAP1R; VIPR1; vasoactive intestinal peptide receptor 1; vasoactive intestinal peptide receptor 1; vasoactive intestinal polypeptide receptor 1; PACAP type II receptor; VIP and PACAP receptor 1; VIP receptor, type I; VPAC1 receptor; pituitary adenylate cyclase activating polypeptide receptor, type II; type 1 vasoactive intestinal peptide receptor; 血管活性肠肽受体-1; 血管活性肠肽受体1(VIPR1);
背景信息:
VPAC1是血管活性肠道肽的受体,这种小神经肽参与调节平滑肌肉松弛,肺部和肠道上皮的水和离子通量,促进神经元生长和生存,调节免疫功能。VPAC1的活性由G蛋白调节,VPAC1与瓜氨酸核苷酸结合蛋白相关膜受体作用,激活腺酸酯环酶。