靶标:
UGT2B4
产品别名:
HLUG25; UDPGT2B4; UDPGTH1; UDPGTh-1; UGT2B11; UGT2B4; UDP glucuronosyltransferase family 2 member B4; UDP glucuronosyltransferase family 2 member B4; UDP-glucuronosyltransferase 2B4; UDP glucuronosyltransferase 2 family, polypeptide B4; UDP-glucuronyltransferase, family 2, beta-4; UDPGT 2B4; hyodeoxycholic acid; hyodeoxycholic acid-specific UDPGT; 尿苷二磷酸葡萄糖醛酸转移酶2B4;
背景信息:
UDP-glucuronosyltransferase (UGT that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of the endogenous estrogen hormones such as estradiol and estriol.