靶标:
TSHR
产品别名:
CHNG1; LGR3; hTSHR-I; TSHR; thyroid stimulating hormone receptor; thyroid stimulating hormone receptor; thyrotropin receptor; TSH receptor; seven transmembrane helix receptor; thyrotropin receptor-I, hTSHR-I; 促甲状腺素受体; 促甲状腺素受体(TSHR); 促甲状腺素受体(C端); 促甲状腺素受体(N端);
背景信息:
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],