靶标:
TRPC6
产品别名:
FSGS2; TRP6; TRPC6; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily C member 6; short transient receptor potential channel 6; TRP-6; focal segmental glomerulosclerosis 2; transient receptor protein 6; 瞬时受体电位离子通道蛋白6; 转化受体电位阳离子通道亚家族C成员6(TRPC6);
背景信息:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009],