靶标:
NR2C1
产品别名:
TR2; NR2C1; nuclear receptor subfamily 2 group C member 1; nuclear receptor subfamily 2 group C member 1; nuclear receptor subfamily 2 group C member 1; TR2 nuclear hormone receptor; orphan nuclear receptor TR2; 核激素受体TR2; 睾丸受体2(TR2);
背景信息:
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],