靶标:
TP53BP2
产品别名:
53BP2; ASPP2; BBP; P53BP2; PPP1R13A; TP53BP2; tumor protein p53 binding protein 2; tumor protein p53 binding protein 2; apoptosis-stimulating of p53 protein 2; BCL2-binding protein; apoptosis-stimulating protein of p53, 2; renal carcinoma antigen NY-REN-51; tumor suppressor p53-binding protein 2; P53凋亡刺激蛋白2;
背景信息:
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],