靶标：
TNFAIP6
产品别名：
TSG-6； TSG6； TNFAIP6； TNF alpha induced protein 6； TNF alpha induced protein 6； tumor necrosis factor-inducible gene 6 protein； TNF-stimulated gene 6 protein； hyaluronate-binding protein； tumor necrosis factor alpha-inducible protein 6； tumor necrosis factor, alpha induced protein 6； tumor necrosis factor-stimulated gene-6 protein； 肿瘤坏死因子α诱导蛋白6(TNFaIP6)；
背景信息：
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010],
