靶标:
SSR1
产品别名:
TRAPA; SSR1; signal sequence receptor subunit 1; signal sequence receptor subunit 1; translocon-associated protein subunit alpha; SSR alpha subunit; SSR-alpha; TRAP alpha; signal sequence receptor subunit alpha; signal sequence receptor, alpha; translocon-associated protein alpha subunit; 易位相关蛋白α/TRAP-α;
背景信息:
Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.